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Treatment & Research

07/05/2003 Author: Drew Provan

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Table of Contents

Latest Treatment and Research at the London

Treatment & Research

Why the need for UK guidelines for ITP?

UK Guidelines

Dr Drew Provan & Prof Adrian Newland

Adult ITP - investigation e.g. bone marrow

Adult ITP - investigation e.g. bone marrow 2

ITP therapies and natural history (outcomes)

Adults: treatment considerations

Adult ITP - “safe” platelet counts

Adults: first line therapy

Adults: second line therapy - drugs

Adults: second line therapy - splenectomy

Indium-labelled platelet scan (Royal London)

Failed splenectomy: what next?

Failed splenectomy: Simple measures

ITP: therapy in adults

UK Guidelines download

Refractory ITP in adults - experimental therapies

Refractory ITP in adults - experimental therapies

Rituximab (anti-CD20)

Rituximab (anti-CD20)

Rituximab (anti-CD20)

Mycophenolate mofetil (MMF) RLH study

Mycophenolate mofetil (MMF)

Selective therapy: CTLA-4-Ig RLH study

CTLA-4-Ig

Thrombopoietin-like agents RLH study

Anti-D RLH study

Infection is implicated in refractory disease

Clinical research collaborations

Why set up registries?

UK Adult ITP Registry

UK Familial ITP Registry

Intercontinental Childhood Study Group

ICIS Registry III

European Haematology Association Working Group

Other collaborations

UK ITP Registry Co-ordinator

UK ITP Registry Co-ordinator

Conclusions 1

Acknowledgements

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