Two Italian ITP Studies 1. Borderline thrombocytopenia 2. Rituximab

23/04/2007


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Table of Contents

Two Italian ITP Studies 1. Borderline thrombocytopenia 2. Rituximab

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How to become an expert in ITP

Research in Italy: The GIMEMA Group

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Background

National Health and Nutrition Examination Survey III

Objective of the study

Study design and setting

Patients

Methods

Age and sex distribution of 260 cases entering 6 mo observation

Platelet distribution of 260 cases entering 6 mo observation

Summary of the results

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Conclusions

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Rituximab Therapy for ITP

Phase I-II trials: Patients’ characteristics*

Phase I-II trials: Results

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Response Duration vs. Type of Response

Patient characteristics based on response to treatment

Duration of ITP and Response

Adverse events

Re-treatment in Relapsed CR/PR Patients

B-cell counts

B-cell Counts: CR vs PR

Median Anti-Platelet-Antibody Titers

Long Term Follow-Up of Patients with Immune Thrombocytopenic Purpura (ITP) Whose Initial Response to Rituximab Lasted a Minimum of 1 Year

Long Term Follow-Up of Patients with Immune Thrombocytopenic Purpura (ITP) Whose Initial Response to Rituximab Lasted a Minimum of 1 Year

Rituximab for adult ITP: Conclusions

Author: Administrator