Table of Contents
Chronic ITP in adults - management issues
Diagnosis and treatment of ITP in adults are not evidence-based
Reasons why choice of treatment is difficult
Difficulty in assessing therapies
Survey of Consultant Haematologists treating adult patients in Rep of Ireland
No of patients with ITP
Investigations
Infectious disease tests
Aim of treatment
Safe platelet count
Threshold for treatment
Cut-off for starting therapy
Change over last 5 years
Same patient, for major surgery
Initial therapy
Therapy
Therapy
Second-line therapies
Splenectomy options
Second line medical therapies
Less commonly used therapies
Other immunosuppression
“New treatments”
Thrombopoietic agents
New therapies
Toxicity of new treatments
Toxicity of new treatments
Conclusion
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