Chronic ITP in adults - management issues

08/08/2005


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Table of Contents

Chronic ITP in adults - management issues

Diagnosis and treatment of ITP in adults are still not evidence-based

Reasons why choice of treatment is difficult

Difficulty in assessing therapies

Survey of Consultant Haematologists treating adult patients in Rep of Ireland

No of patients with ITP

Investigations

PPT Slide

Other investigations

Aim of treatment

Safe platelet count

Threshold for treatment

Cut-off for starting therapy

Change over last 5 years

Same patient, for major surgery

Initial therapy

Therapy

Therapy

Second-line therapies

Splenectomy options

Second line medical therapies

Less commonly used therapies

Other immunosuppression

“New treatments”

Thrombopoietic agents

New therapies

Toxicity of new treatments

Toxicity of new treatments

Conclusion

Author: Gerard Crotty