Side-effects of therapy

• Effects of prolonged steroids:

• Accelerated osteoporosis, espec older women (calcium/vit D/bisphosphonates)

• Occasional profound effects on body image

• Danazol:

• Virilisation/male pattern alopecia/avoid pregnancy (virilised fetus)

• Azathioprine:

• Ideally avoid in pregnancy, but transplant data reassuring

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